What is it about?
The originality of our case is that a microadenoma also may be encountered in KS. Hormonal assessment indicated the microadenoma was non-functioning. This emphasizes the importance of visualizing the pituitary region in KS patients to assess for hypoplastic pituitary malformations or adenomas.
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Why is it important?
The originality of our case is that a microadenoma also may be encountered in KS. Hormonal assessment indicated the microadenoma was non-functioning. This emphasizes the importance of visualizing the pituitary region in KS patients to assess for hypoplastic pituitary malformations or adenomas.
Perspectives
KS is a developmental disorder characterized by the association of isolated hypogonadotropic hypogonadism and anosmia/hyposmia. Olfactory MRI imaging may aid in the diagnosis of KS in patients with suggestive clinical findings. Pituitary adenoma is a rare association with the KS. In our case, it was a non-functional microadenoma. This emphasizes the need to image the pituitary region in KS patients to assess for hypoplastic pituitary malformations or adenomas incidentaloma – as was the case in this patient. Early diagnosis of KS is important to ensure better quality of life
Taieb Ach
Hospital University Farhat Hached Sousse Tunisia
Read the Original
This page is a summary of: A case of Kallmann syndrome associated with a non-functional pituitary microadenoma, Endocrinology Diabetes and Metabolism Case Reports, April 2018, Bioscientifica,
DOI: 10.1530/edm-18-0027.
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A case of Kallmann syndrome associated with a non-functional pituitary microadenoma
KS is a developmental disorder characterized by the association of isolated hypogonadotropic hypogonadism and anosmia/hyposmia. Olfactory MRI imaging may aid in the diagnosis of KS in patients with suggestive clinical findings. Pituitary adenoma is a rare association with the KS. In our case, it was a non-functional microadenoma. This emphasizes the need to image the pituitary region in KS patients to assess for hypoplastic pituitary malformations or adenomas incidentaloma – as was the case in this patient. Early diagnosis of KS is important to ensure better quality of life
A case of Kallmann syndrome associated with a non-functional pituitary microadenoma
The main clinical characteristics of KS include hypogonadotropic hypogonadism and anosmia or hyposmia. MRI, as a non-irradiating technique, should be the first radiological step for investigating the pituitary gland as well as abnormalities of the ethmoid, olfactory bulbs and tracts in KS. KS may include anterior pituitary hypoplasia or an empty sella syndrome. The originality of our case is that a microadenoma also may be encountered in KS. Hormonal assessment indicated the microadenoma was non-functioning. This emphasizes the importance of visualizing the pituitary region in KS patients to assess for hypoplastic pituitary malformations or adenomas.
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