ASIC1a Activation Enhances Inhibition in the Basolateral Amygdala and Reduces Anxiety

What is it about?

In this paper, we provide evidence that ASICs1A are present on GABAergic interneurons in the basolateral amygdala and that their overall function is to reduce excitability within the amygdala.

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Why is it important?

This paper is important because it provide evidence that alterations in the pH of the brain may affect the excitability of the BLA, which, in turn, might lead to alterations in anxiety like behavior.