What is it about?
To estimate the association between ICS and pneumonia among users of ICS relative to non-ICS users and to examine whether this risk is dose related, class related and what's its association with the pneumonia-mortality or overall mortality.
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Why is it important?
THIS A SUBJECT OF DEBATE..AND ICS ARE USED IN ASTHMA AND COPD PATIENTS
Perspectives
ICS alone or in combination with long-acting β-agonists are associated with an increased risk of pneumonia but have no effect on pneumonia related mortality. It is important to identify those patients to benefit the most from ICS, as those with frequent exacerbations, a severe airway obstruction, a positive bronchodilator test or a sputum eosinophilia despite treatment.
Dr Adamantia Liapikou
Sotiria Hospital
Read the Original
This page is a summary of: Managing the safety of inhaled corticosteroids in COPD and the risk of pneumonia, Expert Opinion on Drug Safety, June 2015, Informa Healthcare,
DOI: 10.1517/14740338.2015.1057494.
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