What is it about?
Animal model systems are a prerequisite to understand the physiology of preterm brain development and associated changes in the EEG pattern. We established a non invasive EEG recording technique which can easily applied to freely moving animals. We found typical network activity associated with age across species.
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Why is it important?
The technique as well as the recorded EEG patterns are very similar to the clinical setting. This gives the opportunity to reduce the severity and number of animal experiments. Since many animals are born with a "preterm brain" in comparison to human, a knowledge gap regarding typical EEG patterns and signs of pathophysiology can potentially be addressed by this technique.
Perspectives
Non invasive EEG recordings in combination with analytic tools relying on network activity open up many possibilies for translational aspects of neuroscience.
Nora Vanessa de Camp
Humboldt-Universitat zu Berlin
Read the Original
This page is a summary of: Models for preterm cortical development using non invasive clinical EEG, Translational Neuroscience, December 2017, De Gruyter,
DOI: 10.1515/tnsci-2017-0029.
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