Solenostemma argel ethanol extract had potent hepatoprotective effects

What is it about?

Solenostemma argel ethanol extract had potent hepatoprotective effects against ethanol-induced hepatotoxicity in rats. This extract inhibited the hepatic damage accompanied by decreased activity of serum liver enzymes. Treatment with S argel extract resulted in restoration of GSH and GST, the antioxidant defense system, which was impaired by ethanol exposure, and suppressed LPO and PC. Furthermore, the protective effect of S argel against ethanol-induced hepatotoxicity demonstrated by the significant reduction of TNF-α, NO and CYP2E1 in liver tissue. Further studies should be done to develop S argel as a new and promising dietary supplement for protection against ethanol-induced liver damage.

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