What is it about?
In this study we assessed the distribution of the genotypes of FSHR Ser680Asn and of AMHRII -482A>G gene polymorphisms in a group of 126 infertile women and a control group of 100 fertile women by using real-time polymerase chain reaction (RT-PCR).
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Why is it important?
The study showed that FSH and AMH correlated levels in certain cases could be used to estimate a patient's ovarian reserve.
Perspectives
There was evidence that in specific subgroups of women undergoing IVF/ICSI, FSHR and AMH SNPs may be related to patients' characteristics and controlled ovarian stimulation and pregnancy outcome and thus may provide a means for the prediction of ovarian response in specific subgroups of women entering an IVF/ICSI program.
Dimitris Loutradis
Read the Original
This page is a summary of: Combined study on the single nucleotide polymorphisms in the follicle-stimulating hormone receptor (Ser680Asn) and anti-Müllerian hormone receptor type II (−482A>G) as genetic markers in assisted reproduction, Hormone Molecular Biology and Clinical Investigation, March 2019, De Gruyter,
DOI: 10.1515/hmbci-2018-0077.
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