What is it about?
The publication describes the synthetic routes to novel thiophene analogs which are likely to become potential anti-cancer compounds as shown by their interesting anti-cancer aitivity.
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Why is it important?
The molecules reported in this communication have shown significant anti-cancer activity and are likely to become clinical candidates if proved in the preclinical studies.
Perspectives
They have potential to be modified into more active compounds by suitable modifications of the scaffold using Structure Activity Relationship studies.
Dr sharma veera raghava Ganapavarapu
GITAM University
Read the Original
This page is a summary of: Design and synthesis of 4,5-diaryl/heteroarylthiophene-2-carboxylic acid derivatives and evaluation of their biological activities, Heterocyclic Communications, January 2017, De Gruyter,
DOI: 10.1515/hc-2016-0131.
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