What is it about?
Role of PARP inhibitors in cancer therapy and medicinal chemistry of current PARP inhibitors
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Why is it important?
DNA damage repair process is maintained by enzyme called PARP. over expression of PARP leads to BRACA and non BRACA mutated cancers
Perspectives
PARP inhibitors could be very important for future cancer therapy and can be also useful as single chemotherapeutic agents in BRACA and non BRACA mutated cancers
Ashish Shah
Sumandeep Vidyapeeth University
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This page is a summary of: A Review on DNA Repair Inhibition by PARP Inhibitors in Cancer Therapy, Folia Medica, March 2018, De Gruyter,
DOI: 10.1515/folmed-2017-0067.
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