What is it about?
Lipid nanogel could be employed to prolong and target miconazole nitrate to the oromucosal layers, minimizing its associated side effects while enhancing its lethality against resistant Candida albicans. In this study, novel lipid nanogels encapsulating MN were developed and evaluated for improved treatment of oropharyngeal candidiasis.
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Why is it important?
Our findings show that the activity of miconazole nitrate against oral thrush swab of Candida albicans can be improved by formulation as tailor-made mucoadhesive lipid nanogel. Thus this developed nanomedicine could be exploited as an alternative therapeutic carrier for the effective treatment of oropharyngeal candidiasis.
Perspectives
Writing this paper was a great pleasure as it brings my research on nanomedicine to bare to the international community via European Journal of Nanomedicine. More so, this article has co-authors with whom I have had long standing collaborations. This research paper also led to nanomedicines research groups contacting me and ultimately to a greater involvement in nanomedicine research for treatment of infectious diseases.
Franklin Kenechukwu
University of Nigeria
Read the Original
This page is a summary of: Tailor-made mucoadhesive lipid nanogel improves oromucosal antimycotic activity of encapsulated miconazole nitrate, European Journal of Nanomedicine, October 2017, De Gruyter,
DOI: 10.1515/ejnm-2017-0010.
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