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Over the past 20 years, interest has grown in the clinical value of cardiac biomarkers for diagnosing and prognosticating a range of pediatric conditions. As recently confirmed, the key takeaway is the urgent need for pediatric-specific validation studies to establish appropriate interpretive frameworks, clinical decision limits, and outcome-driven guidance for cardiac troponin testing in children.

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This page is a summary of: Cardiac troponin in pediatric cardiology: toward standardized interpretive frameworks and clinical decision limits, Clinical Chemistry and Laboratory Medicine (CCLM), September 2026, De Gruyter,
DOI: 10.1515/cclm-2026-1248.
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