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Urine samples from patients with adrenal tumors were analyzed by untargeted metabolomics. We identified several steroid conjugates as potential novel biomarkers for adrenocortical carcinoma and highlight limitations of enzymatic steroid hydrolysis.

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This page is a summary of: An untargeted metabolomics approach to evaluate enzymatically deconjugated steroids and intact steroid conjugates in urine as diagnostic biomarkers for adrenal tumors, Clinical Chemistry and Laboratory Medicine (CCLM), January 2025, De Gruyter,
DOI: 10.1515/cclm-2024-1337.
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