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Quantitative measurement of HBV DNA levels in the plasma/serum has become a key test for confirmation of HBV infection and monitoring of HBV-infected patients during therapy. The new TMA based Aptima HBV-assay from Hologic could be shown to be a highly sensitive, accurate, and reproducible new assay with performance equal to that of the established reference assay HPS/CTM from Roche. This is the first evaluation comparing the performance of Aptima and HPS/CTM.

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This page is a summary of: Evaluation of the Aptima HBV Quant assay vs. the COBAS TaqMan HBV test using the high pure system for the quantitation of HBV DNA in plasma and serum samples, Clinical Chemistry and Laboratory Medicine (CCLM), December 2017, De Gruyter,
DOI: 10.1515/cclm-2017-0701.
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