What is it about?
Most women with epithelial ovarian cancer are diagnosed at advanced stage. The main goal for these patients is to determine the best therapeutic strategy for initial management: primary debulking surgery vs neoadjuvant chemotherapy followed by interval debulking surgery. Conventional staging methods such as serum markers (CA-125, CEA) or computed tomography are not accurate enough to predict complete resectability. The role of laporoscopy is increasing in ovarian cancer and it appears to be the most accurate tool for triaging patients with advanced disease for primary surgery vs neoadjuvant chemotherapy.
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Why is it important?
Despite maximal surgical effort, complete resection (that is absence of gross residual tumor) is not always achievable in patients with advanced epithelial ovarian cancer. This review highlights the accuracy of laparoscopic-based models in predicting resectability and response after treatment in advanced ovarian cancer.
Perspectives
In my opinion, gynecologic oncologists should consider to incorporate laparoscopy into the standard of care of patients with advanced-stage epithelial ovarian cancer since it is the best predictor of resectability so far.
Natalia Zeff
Institute of Oncology "Angel H. Roffo"
Read the Original
This page is a summary of: Role of laparoscopy in initial tumour staging in advanced epithelial ovarian cancer: a systematic review, Pleura and Peritoneum, March 2018, De Gruyter,
DOI: 10.1515/pp-2018-0106.
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