Growth velocity and biological variables during puberty in achondroplasia

Mariana del Pino, Virginia Fano, Paula Adamo
  • Journal of Pediatric Endocrinology and Metabolism, March 2018, De Gruyter
  • DOI: 10.1515/jpem-2017-0471

Puberty in achondroplasia

What is it about?

Achondroplasia is the most common form of inherited disproportionate short stature. There is a lack of knowledge about growth in height and milestones during puberty for children with Achondroplasia.

Why is it important?

In boys the mean adult height was 129.18 cm. Age and velocity at peak velocity in puberty were 13.89 yr and 4.86 cm/yr respectively. The adolescent gain was 20.40 cm. In girls the mean adult height was 118.67 cm. Age and velocity at peak velocity in puberty were 11.45 yr and 4.40 cm/yr respectively. The adolescent gain was 19.35 cm. Achondroplasia children experienced an adolescent growth spurt and it was similar in shape and half the magnitude of non-Achondroplasia population.

Perspectives

Mariana del Pino (Author)
Hospital de Pediatria Garrahan

Writing this article was a great pleasure as it has co-authors with whom I have had long standing working. This article also lead to achondroplasia, to a greater involvement in rare disease research.

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http://dx.doi.org/10.1515/jpem-2017-0471

The following have contributed to this page: Mariana del Pino