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A unique interference has been reported, based on the presence of a circulating monoclonal protein. The interference simulated the presence of a severe inflammation, and led to unnessary clinical investigations.

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This page is a summary of: Increased C-reactive protein values in the absence of inflammation: monoclonal immunoglobulin interference in immunonephelometry, Clinical Chemistry and Laboratory Medicine (CCLM), June 2019, De Gruyter,
DOI: 10.1515/cclm-2019-0398.
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