Do Ambient Ozone or Other Pollutants Modify Effects of Controlled Ozone Exposure on Pulmonary Function?

What is it about?

We previously found that 3 hours of controlled exposure ozone (120ppb and 70ppb) caused reductions in lung function with evidence for airway inflammation and injury. We then assessed whether subjects' exposures to indoor and outdoor air pollution in the hours and days before each controlled ozone exposure modified this response. The reductions in lung function markers following controlled ozone exposure were observed only when ambient nitrogen dioxide and carbon monoxide, and personal nitrogen dioxide concentrations were high in the hours and days before the controlled ozone exposures.

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