Between-Visit Variability in FEV1 as a Diagnostic Test for Asthma in Adults

Benjamin W. Dean, Erin E. Birnie, George Alex Whitmore, Katherine L. Vandemheen, Louis-Philippe Boulet, J. Mark FitzGerald, Martha Ainslie, Samir Gupta, Catherine Lemiere, Stephen K. Field, R. Andrew McIvor, Paul Hernandez, Irvin Mayers, Shawn D. Aaron
  • Annals of the American Thoracic Society, September 2018, American Thoracic Society
  • DOI: 10.1513/annalsats.201803-211oc

What is it about?

Our study results indicate that a 12 percent and 200 mL between-visit variation in FEV1 has poor sensitivity but good specificity for diagnosing asthma. Poor sensitivity suggests that only a small proportion of patients with asthma will be successfully diagnosed using this test.

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