What is it about?
40% of POTS adolescents demonstrate a hyperkinetic circulation during exercise which we attribute this to failure of normal regional vasoconstriction during dynamic exercise. Patients must increase flow through an inappropriately vasodilated systemic circulation to maintain BP.
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Why is it important?
Patients with orthostatic intolerance who meet case definition of postural orthostatic tachycardia have a more pervasive disturbance in regulation of circulation.
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This page is a summary of: High flow variant postural orthostatic tachycardia syndrome amplifies the cardiac output response to exercise in adolescents, Physiological Reports, August 2014, Wiley,
DOI: 10.14814/phy2.12122.
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