What is it about?
This study assesd nucleophosmin gene subcellular localisation and expression during proliferation of AML cell line cells in a trial to find out its proliferative effect
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Why is it important?
This the first study that showed a pro-proliferative effect of nucleophosmin gene mutations on AML cell line cells
Perspectives
This study high lighted the importance of thinking about mutated nucleophosmin as an important molecular target during development of new targeted therapies for AML
Dr Safaa AA Khaled
Hematology and BMT unit, Department of Internal Medicine, Assiut University Hospital
Read the Original
This page is a summary of: Role of Nucleophosmin Gene Mutation in Leukemogenesis of Acute Myeloid Leukemia, Journal of Hematology, January 2018, Elmer Press, Inc.,
DOI: 10.14740/jh365w.
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