What is it about?
In this observational study, we found that blood levels of protein called cardiac troponin (the current standard test used clinically to measure heart damage) measured with a high-sensitivity assay do not change during a stress test, even if a patient has evidence of reversible heart disease during their test.
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Why is it important?
Some cardiologists have suggested that any significant coronary artery disease leading to myocardial ischemia would demonstrate elevations of cardiac troponin using a high sensitivity assay. This study shows that, in fact, it is possible to have myocardial ischemia without significant changes in high sensitivity cardiac troponin levels.
Read the Original
This page is a summary of: Myocardial Ischemia on Exercise Stress Echocardiography Testing Is Not Associated with Changes in Troponin T Concentrations, The Journal of Applied Laboratory Medicine, January 2017, AACC,
DOI: 10.1373/jalm.2016.021667.
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