Alkaline Ceramidase 3 Deficiency Results in Purkinje Cell Degeneration and Cerebellar Ataxia Due to Dyshomeostasis of Sphingolipids in the Brain

What is it about?

A new gene has been discovered to produce balance difficulties in older mice by causing changes in the balance of particular fats within the brain.

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Why is it important?

There are many genes that are known to cause problems with balance in humans, and this may be another gene that affects humans. Understanding the different causes for this health issue will help lead to treatment options.