What is it about?

Rats' reaction to gloved hand in cage using ultrasonic vocalization

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Why is it important?

To enhance animals' welfare (3Rs principle)


For the first time, we observed rats respond to gloved hand with negative vocalization. In animal handling, hand intrusion should be reduced. or acclimated to reduce animals stress and increase the study result quality.

Chang-Ning liu
Pfizer Inc

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This page is a summary of: Introduction of gloved hand to cage induces 22-kHz ultrasonic vocalizations in male albino rats, PLoS ONE, November 2022, PLOS,
DOI: 10.1371/journal.pone.0278034.
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