What is it about?

We aimed to test and validate a subscale of an existing health related quality of life (HRQoL) instrument among patients with acute blast or gunshot wounds. We used data from a randomized controlled trial comparing negative pressure wound therapy with standard treatment of civilian adults with acute extremity blast or gunshot wounds. We evaluated the reliability (internal consistency, stability) and validity of the body subscale of the Wound QoL instrument using the World Health Organisation 20 question self-reporting questionnaire as gold standard. A total of 152 participants were included in the study. The participants were predominantly (93.4%) male, and median age was 29.0 years (IQR 21.0–34.0). The internal consistency was acceptable while a test-retest analysis indicated instability in the Wound QoL instrument. The content validity of the instrument was considered satisfactory; however, the criterion validity was found to be insufficient.

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Why is it important?

Acute blast or gunshot wounds have a negative effect on the patients’ HRQoL. No validated instrument exists to assess the HRQoL of patients with such wounds.


Our results indicate that Wound QoL is a promising instrument for the assessment of wound specific HRQoL among patients with acute blast or gunshot wounds.

Andreas Älgå
Karolinska Institutet

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This page is a summary of: Wound specific quality of life after blast or gunshot injury: Validation of the wound QoL instrument, PLoS ONE, October 2022, PLOS, DOI: 10.1371/journal.pone.0277094.
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