What is it about?

Because bowel gas deteriorates the image quality of abdominal ultrasonography (AUS), it is common to perform AUS prior to esophagogastroduodenoscopy (EGD). This one-way order limits the availability of examination appointments. To evaluate whether EGD using insufflation of carbon dioxide (CO2), which is rapidly absorbed by the gastrointestinal mucosa, preserves the image quality of AUS performed subsequently, we designed a non-inferiority test in which each subject underwent AUS, EGD with CO2 insufflation, and a second AUS, in that order.

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Why is it important?

The use of CO2 for insufflation in EGD does not cause much deterioration in the image quality of AUS performed subsequently. Therefore, it is permissible to perform EGD prior to AUS, which is expected to improve the efficiency of examination setup.

Perspectives

In addition to the results of this research, I was also interested in the discussion with the reviewer on the statistical examination. I would like everyone to take a look at the published peer review.

Yukihiro Shirota
Saiseikai Kanazawa Hospital

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This page is a summary of: Image quality of abdominal ultrasonography after esophagogastroduodenoscopy is preserved by using carbon dioxide insufflation: A non-inferiority test in the same subject, PLoS ONE, September 2022, PLOS,
DOI: 10.1371/journal.pone.0275257.
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