What is it about?

Raised serum C-peptide than raised Lp(a) can be a prior predictor for cardiometabolic disease risk in healthy participants and patients with T2DM with increased cardiometabolic biomarkers. Case and control males and females with visceral obesity are exposed to increased C-peptide.

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Why is it important?

Association of C-peptide and lipoprotein (a) as two novel predictors with cardiometabolic biomarkers in patients with type 2 diabetes were demonstrated. Therefore, reducing raised serum C-peptide and Lp(a) levels with strict control of LDL-C together with weight reduction would be the best approach to prevent CAD consequences.

Perspectives

Monitoring of patients with type 2 diabetes and seemingly healthy individuals to prevent CVD consequences such as myocardial infarction is a critical public health issue for the health of the global community.

Mohammad Reza Mahmoodi
Kerman University of Medical Sciences

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This page is a summary of: Association of C-peptide and lipoprotein(a) as two predictors with cardiometabolic biomarkers in patients with type 2 diabetes in KERCADR population-based study, PLoS ONE, May 2022, PLOS,
DOI: 10.1371/journal.pone.0268927.
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