What is it about?
Many reports have shown that sarcopenia strongly correlated with a poor prognosis. However it is unknown whether sarcopenia increases lung cancer recurrence. This study was to evaluate whether sarcopenia directly increases recurrence and whether it suppresses anti-tumor immunity in patients with lung cancer.
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Why is it important?
The 5-year recurrence rate in patients with sarcopenia was significantly higher than those without sarcopenia. Tumor immunity in saccopenia patients have rich in tumor-associated macrophages which promote tumor progression and metastasis.
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This page is a summary of: Sarcopenia increases the risk of post-operative recurrence in patients with non-small cell lung cancer, PLoS ONE, September 2021, PLOS, DOI: 10.1371/journal.pone.0257594.
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