What is it about?

We measured how well tulathromycin susceptibility test results predicted tulathromycin treatment success or failure of bovine respiratory disease.

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Why is it important?

Antimicrobial susceptibility testing is considered the "gold standard" for choosing the most effective antibiotic. However, the complex disease process of bovine respiratory disease puts a test for a single bacteria at a clear disadvantage.


Antibiotics help kill bacteria as does a healthy immune response. A laboratory based test cannot measure the animal's immune response so it is not a surprise that antimicrobial susceptibility test results poorly predicted clinical outcome of BRD.

Dr. Jeffrey James Sarchet
Zoetis Inc

Read the Original

This page is a summary of: Limitations of bacterial culture, viral PCR, and tulathromycin susceptibility from upper respiratory tract samples in predicting clinical outcome of tulathromycin control or treatment of bovine respiratory disease in high-risk feeder heifers, PLoS ONE, February 2022, PLOS, DOI: 10.1371/journal.pone.0247213.
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