What is it about?
HIV-1 has had a great impact on Brazil and Brazilians over the past thirty years. This article provides virological and immunological perspectives on how the disease affects the Brazilian population and how Brazilians react to the available anti-retroviral therapies available. Finally, we treat the important issue of emerging drug resistant mutations that will cause therapeutic failures and the necessity to change medications.
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Why is it important?
As all researchers drive towards control and a cure for HIV, we need to keep our research grounded in the reality of what the disease is. This article helps with this and provides a background to orient our searches.
Perspectives
This article offered an opportunity to get stuck into the details of HIV-1 research in Brazil and to get up to speed on how the disease affects the population here. My role in the research was primarily the quantitative analysis.
Dr. James R Hunter
UNIFESP
Read the Original
This page is a summary of: The Virological and Immunological Characteristics of the HIV-1-Infected Population in Brazil: From Initial Diagnosis to Impact of Antiretroviral Use, PLOS One, October 2015, PLOS,
DOI: 10.1371/journal.pone.0139677.
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Contributors
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