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Sri Lankan Ayurveda clinical practice Satapushpa Shatavari powder (SSP) with or without Satapushpa Shatavari Grita (SSG) enema is used for manage menstrual disturbances due to polycystic ovary syndrome (PCOS). Objective of Present study was to evaluate the efficacy of Satapushpa Shatavari Churna with Satapushpa Shatavari Grita Matra Vasti for the management of PCOS by an open label comparative clinical trial. Successful screening 60 PCOS participants were randomly divided into three groups (n = 20) viz Group A (Oral Administration of SSP 05g t. d. s. with 10 ml of cows ghee for 2 weeks), Group B (Rectal Administration of SSG as enema, 60 ml / day for 2 weeks with 1 week gap) and Group C (oral and rectal administration of SSP and SSG drugs respectively). After one month administration period participants in group A, B and C were assessed on PCOS appearance of the ovary, volume of the ovary, endometrial thickness by US scan. Further volume of menstrual flow, intermenstrual period and hirsutisum was assessed by standard scoring system. The study revealed that all treated groups were reduced their ovarian volumes when compare with pretreated stages. Endometrial thickness of each groups were improved and group C was shown significant improvement. Hirsutisum ratings score was significantly improved in group C. Quantities of the menstruation of all drug treated groups were significantly improved. The findings of the present study indicate that SSP therapy leads to comparable reduction of ovarian volume in a manner, which correlates with the degree of reduction of PCOS and related signs.

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This page is a summary of: , International Journal of Pharmaceutical Sciences and Research, June 2018, International Journal of Pharmaceutical Sciences and Research,
DOI: 10.13040/ijpsr.0975-8232.9(6).2494-99.
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