What is it about?

Diabetic foot ulcerations are notorious in difficulty to heal for a variety of reasons, with a myriad of complications if left untreated. We utilize two allografts in conjunction in order to promote accelerated healing of complicated multifactorial diabetic foot ulcerations. The dehydrated amniotic allograft is supplemented with the cross-linked collagen and glycosaminoglycan matrix in order to maximize healing potential.

Featured Image

Why is it important?

This is the first study that reports the use of a combination of two allografts in conjunction to accelerate healing of complicated diabetic foot ulcerations. We have found that our therapy is significantly more effective than traditional wound debridement and local wound care.


As foot and ankle specialists complicated diabetic foot ulcerations are some of the greatest challenges we encounter everyday in our practices. The techniques discussed and use of two distinctly different allografts in conjunction will provide another tool in the arsenal utilized to treat these challenges. We hope that other practitioners try to utilize our approach in their practice.

Daniel Zilberbrand
Mount Sinai Health System

Read the Original

This page is a summary of: Healing hard-to-heal diabetic foot ulcers: the role of dehydrated amniotic allograft with cross-linked bovine-tendon collagen and glycosaminoglycan matrix, Journal of Wound Care, July 2021, Mark Allen Group, DOI: 10.12968/jowc.2021.30.sup7.s47.
You can read the full text:



The following have contributed to this page