What is it about?
Reviews recent findings about how cells make the decision to divide.
Featured Image
Why is it important?
Entry into the cell division cycle is tightly regulated and becomes misrelated in cancer cells. Recent work has added to our understanding of this critical transition, and refined earlier, simple models of how and when pro- and anti-proliferative signals are integrated to make the decision to divide (or not). These studies have raised new questions, however, and future work is needed to reconcile differences between models derived from different approaches or in different cell types.
Read the Original
This page is a summary of: Getting to S: CDK functions and targets on the path to cell-cycle commitment, F1000Research, September 2016, Faculty of 1000, Ltd.,
DOI: 10.12688/f1000research.9463.1.
You can read the full text:
Contributors
The following have contributed to this page
