Statistical analysis plan of the Benefits and Risks of Iron interventionS in Children (BRISC) trial.

What is it about?

The Benefits and Risks of Iron interventionS in Children (BRISC) trial will evaluate the impact of universal supplementation with iron supplements or iron-containing multiple micronutrient powders (MNPs) compared with placebo given for 3 months on child development, growth, morbidity, laboratory indices of anaemia, iron deficiency, and inflammation at end of intervention and after a further 9 months post intervention in children aged 8 months living in rural Bangladesh. This paper describes the statistical analysis plan.

Featured Image

Why is it important?

A detailed statistical analysis plan published prior to unblinding the allocated treatments will support the statistical analyses and reporting to be undertaken after unblinding. It allows for transparency as well as reproducibility of statistical analyses and reporting.