What is it about?
Antenatal corticosteroids are an essential component in the management of women at risk for preterm labour. They promote lung maturation and reduce the risk of other preterm neonatal complications. This narrative review discusses the contentious issues and controversies around the optimal use of antenatal corticosteroids and their consequences for both the mother and the neonate. The most recent evidence-base is presented.
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Why is it important?
The review identifies where the benefit of steroids is clear and where further evidence is needed to determine the risk and benefit. The current international guidelines are discussed.
Perspectives
This review is helpful for obstetricians, endocrinologist and paediatricians. The role of antenatal corticosteroids at different gestations, in twin pregnancy, the steroid timing and regimen and the potential for harm is discussed. A comparative table of current guidelines is presented.
Katie Wynne
University of Newcastle
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This page is a summary of: Antenatal corticosteroid administration for foetal lung maturation, F1000Research, March 2020, Faculty of 1000, Ltd.,
DOI: 10.12688/f1000research.20550.1.
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