What is it about?

Healthy subjects performing exercise have modest oxidative stress and no alteration of muscle excitability. The association of enhanced oxidative stress and altered muscle excitability seems characteristics of patients with the Chronic Fatigue Syndrome.

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Why is it important?

Dysregulation of muscle function supports the biological basis of the Chronic Fatigue Syndrome which does not result from psychiatric disorders

Perspectives

Because muscle disorders persist after exercise trial they could partly explain the occurrence of post-exertional malaise in numerous patients with Chronic Fatigue Syndrome

Yves Jammes

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This page is a summary of: Understanding neuromuscular disorders in chronic fatigue syndrome, F1000Research, November 2019, Faculty of 1000, Ltd.,
DOI: 10.12688/f1000research.18660.1.
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