What is it about?

Spironolactone has been around for 60 years. In terms of the roles of Mineralocorticoid Receptor Antagonists (MRAs) , we have just scratched the surface: watch this space.

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Why is it important?

Because there is increasing evidence, for example, that hyperaldosteronism may play a significant role in over 50% of hypertension, for example.

Perspectives

It's exciting times, but there is an element of attempting to turn around the Queen Mary.

John Funder
Hudson Institute

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This page is a summary of: Spironolactone in cardiovascular disease: an expanding universe?, F1000Research, September 2017, Faculty of 1000, Ltd.,
DOI: 10.12688/f1000research.11887.1.
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