Viral diesease pathways inhibiting Immune response
What is it about?
This publication highlights a common entry route used by several viruses to infect human hosts. Their entry pattern subdues related genetic pathways leading to inhibition of Major Histocompatibility Class I genes.
Why is it important?
This work brings to light the role of LCK a key gene whose role is critical to viral inhibition but viral pathogens turn to control its splicing machinery rendering it non functional. This will guide new therapeutic decisions addressed by our group
The following have contributed to this page: Dr Daniel A Achinko, Dr Muneer Abbas, and Dr Anton Dormer