What is it about?

Vaccinations are often followed by adverse effects, sometime serious, but establishing a causal link is difficult. The WHO guidelines are universally adopted, but there are several problems in their application.

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Why is it important?

The correct approach to causality assessment is important for the evaluation of cost/benefit ratio of vaccines and for compensation of persons who have suffered serious consequences.

Perspectives

I hope that this paper may become useful for a correct application of WHO guidelines of causality assessment of AEFI.

Paolo Bellavite
University of Verona

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This page is a summary of: Causality assessment of adverse events following immunization: the problem of multifactorial pathology, F1000Research, March 2020, Faculty of 1000, Ltd.,
DOI: 10.12688/f1000research.22600.1.
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