What is it about?
DNA samples are now routinely sequenced. However, when performing an experiment it is possible that a sample may become contaminated with DNA from an unknown origin. FastQ Screen helps users identify the source, or sources, of DNA present in a sample.
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Why is it important?
Failure to detect contamination, or sample swaps, can lead to incorrect conclusions being drawn on experimental results.
Perspectives
Prior to complex analysis it is imperative that a DNA sample has passed the necessary quality control checks. We recommend incorporating FastQ Screen into such quality control workflows.
Steven Wingett
Babraham Institute
Read the Original
This page is a summary of: FastQ Screen: A tool for multi-genome mapping and quality control, F1000Research, August 2018, Faculty of 1000, Ltd.,
DOI: 10.12688/f1000research.15931.1.
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