What is it about?
Patients with acromegaly have calcium and bone problems. We studied a group of patients with acromegaly and a control group in order to better understand these problems. In addition, we clarified the effect of acromegaly treatment on calcium and bone metabolism markers.
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Why is it important?
Our findings indicate that calcium and bone metabolism problems are common in acromegaly patients. Increased awareness and understanding of these abnormalities may reduce long-term complications including vertebral compression fractures and kidney stones.
Perspectives
The health issues derived from calcium and bone changes in patients with acromegaly have long-term implications. Some resolve after acromegaly is controlled, some are persistent. It is important to diagnose acromegaly early, so treatment is delivered in a timely fashion and complications minimized. There is no specific medical treatment for compression fractures that occur even many years after diagnosis made. This article is a step forward in understanding the possible mechanisms. Further research in this field is necessary.
Dr. Adriana G Ioachimescu
Emory University
Read the Original
This page is a summary of: Calcium and Bone Turnover Markers in Acromegaly: A Prospective, Controlled Study, The Journal of Clinical Endocrinology & Metabolism, April 2017, Endocrine Society,
DOI: 10.1210/jc.2016-3693.
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