What is it about?
There is some concern that glucose homeostasis is impaired in girls with Turner's syndrome treated with Growth Hormone (GH) . We evaluated HOMA , oral disposition and insulinogenic indexes in a large group of these girls and we showed that , during a long follow up ( 7 years), glucose homeostasis was not impaired by GH.
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Why is it important?
We have evaluated both static and dynamic indexes of glucose homeostasis, during a long follow up. We could conclude that our results are reassuring about the risk of diabetes in TS girls treated with GH, and that a regular evaluation of glucose homeostasis by oral glucose tolerance test may be necessary only in selected cases
Perspectives
I hope this article would contribute to help colleagues in the management of girls with Turner's syndrome. Writing this article was a great pleasure and a good chance to collaborate with the major experts in this field.
dr Federico Baronio
Universita degli Studi di Bologna Azienda Ospedaliera Sant'Orsola-Malpighi
Read the Original
This page is a summary of: The influence of GH treatment on glucose homeostasis in girls with Turner Syndrome: a 7 years study, The Journal of Clinical Endocrinology & Metabolism, December 2016, Endocrine Society,
DOI: 10.1210/jc.2016-3179.
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