What is it about?
This paper reports the findings that estradiol is synthesized in the Peyer's patch and mesenteric lymph node and plays important role in lymphocyte homeostasis regulation.
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Why is it important?
This is the first discovery that estradiol is synthesized in the secondary lymphoid tissue and its potential important role in the digestive system.
Perspectives
This paper is expected to lead to many important discoveries on the role of estradiol in regulating gut immune system and therefore its application in treating intestinal diseases.
Dr. Chemyong Ko
University of Illinois at Urbana-Champaign
Read the Original
This page is a summary of: Estradiol Synthesis in Gut-Associated Lymphoid Tissue: Leukocyte Regulation by a Sexually Monomorphic System, Endocrinology, December 2016, Endocrine Society,
DOI: 10.1210/en.2016-1391.
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