What is it about?

leptin action and signal transduction in the hypothalamus

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Why is it important?

identify that leptin behaves as pro-inflammatory cytokine on centers of food intake

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This page is a summary of: Leptin and Tumor Necrosis Factor-  Induce the Tyrosine Phosphorylation of Signal Transducer and Activator of Transcription Proteins in the Hypothalamus of Normal Rats In Vivo, Endocrinology, July 2001, Endocrine Society, DOI: 10.1210/en.142.7.3027.
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