What is it about?

Developing neonatal rat lungs were treated with high doses of glucocorticoids. The result was that there was precocial maturation of the lung exchange tissue.

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Why is it important?

he result was that there was precocial maturation of the lung exchange tissue, a good effect in mitigation of respiratory distress syndrome.

Perspectives

Investigations in future should search for molecules with less deleterious effects.

Professor Andrew N Makanya
University of Nairobi

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This page is a summary of: Effects of Neonatal High-Dose Short-Term Glucocorticoid Treatment on the Lung: A Morphologic and Morphometric Study in the Rat, Pediatric Research, January 2003, Nature,
DOI: 10.1203/00006450-200301000-00014.
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