Atherosclerotic lesions are acidic - here's an explanation why
What is it about?
Atherosclerotic lesions have areas that are acidic. We and others have been examining how this influences the atherosclerotic lesions. It actually seems that acidic pH increases lipid accumulation in the lesions, increases inflammation, and decreases the good effects of HDL particles. This review article collected all the information in one article.
Why is it important?
It seems that acidic pH can make atherosclerosis worse. It is important to know the conditions in the lesions and how they influence progression of the disease. The lesions that are particularly acidic may be the ones that cause symptoms - therefore it would be important to know how and why and what can we do to prevent this.
The following have contributed to this page: Dr Katariina Öörni