What is it about?
nicotinic acid or niacin, which is used in human patients with dyslipidemia, lowers Lp(a) by reducing apoA hepatic expression and thus reduces cardio vascular risk
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Why is it important?
nicotinic acid is the only approved drugs in human able to lower Lp(a) and apoA expression
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This page is a summary of: Nicotinic acid inhibits hepaticAPOAgene expression: studies in humans and in transgenic mice, Journal of Lipid Research, August 2012, American Society for Biochemistry & Molecular Biology (ASBMB),
DOI: 10.1194/jlr.m029769.
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