What is it about?
We aimed to assess the frequency of neuropathic pain in primary KOA patients (using clinical questionnaires) and to investigate its correlation with socio-demographic factors, physical function, quality of life, disease severity, and serum beta nerve growth factor (β-NGF) levels.
Featured Image
Photo by Europeana on Unsplash
Why is it important?
People with KOA may present with different pain phenotypes, including nociceptive, inflammatory, and neuropathic pains. Neuropathic component of OA pain, possibly emerging from peripheral and central pain sensitization mechanisms. Even though serum-NGF levels are increased in KOA patients, their probable links to neuropathic pain have never been investigated. Therefore, we aimed to assess serum β-NGF levels in patients with KOA and neuropathic pain compared to those with non-neuropathic pain.
Perspectives
I hope this study supports a more personalized approach to managing knee osteoarthritis.
Professor shereen refaat kamel
Minia University
Read the Original
This page is a summary of: Neuropathic pain in primary knee osteoarthritis patients: correlation with physical function, quality of life, disease severity, and serum beta nerve growth factor levels, Egyptian Rheumatology and Rehabilitation, November 2021, Springer Science + Business Media,
DOI: 10.1186/s43166-021-00086-x.
You can read the full text:
Contributors
The following have contributed to this page
