What is it about?
the GLR, GLRF, and their hot-water extracts with prebiotic and immune-stimulatory activities could be processed as feed additives which could increase the waste-recycling.
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Why is it important?
It was estimated that several thousand tons of residues of Ganoderma lucidum (GLR) were discarded. HWP_GLR and HWP_GLRF with molecular size 5 to 8 kDa were showed to stimulate growths of L. rhamnosus and B. longum. It was found that in the presence of polymyxin B HWP_GLR and HWP_GLRF could stimulate nitric oxide productions, elevate phagocytic activities against FITC-labeled E. coli, and to lower lipopolysaccharide-binding capacities in RAW264.7 cells. The broiler chicks were selected for feedings in vivo. The one-day-old chicks were fed commercial feeds for one week, and then were fed without or with 4% or 8% of GLR and GLRF additives for three weeks. There was no significant weight difference among feeding groups. However, the phagocytosis and natural killer cytotoxicity in the peripheral bloods, and prebiotic activities of bifidobacteria in feces of GLR and/or GLRF groups were significantly different compared to the control (P < 0.05).
Perspectives
It might be possible to add anti-bacterial properties of herbal medicines with GLR or GLRF to develop the new functional feeds with prebiotic, immune-stimulatory and anti-bacterial activities to reduce the uses of antibiotics and needed further investigations.
Professor Wen-Chi Hou
Taipei Medical University
Read the Original
This page is a summary of: Effects of hot-water extracts from Ganoderma lucidum residues and solid-state fermentation residues on prebiotic and immune-stimulatory activities in vitro and the powdered residues used as broiler feed additives in vivo, Botanical Studies, July 2015, Springer Science + Business Media,
DOI: 10.1186/s40529-015-0097-3.
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