What is it about?
For the first time, MIC of siderophores (Exochelin MS and Deferoxamine B) has been determined using the MGIT-DST method for drug-resistant Mycobacterium tuberculosis isolates.
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Why is it important?
Mycobacterium tuberculosis has acquired resistance over the years. Alternative treatment with siderophore such as FDA approved deferoxamine B, to overcome the problem of drug-resistant Mycobacterium tuberculosis.
Perspectives
This study has provided a “proof of concept” that exogenous siderophores such as Exo-MS and DFO-B could be valuable additions to fight drug-resistant M. tuberculosis.
Dr. Karuna Gokarn
Sir HN Reliance Foundation Hospital and Research Centre
Read the Original
This page is a summary of: Preliminary evaluation of anti-tuberculosis potential of siderophores against drug-resistant Mycobacterium tuberculosis by mycobacteria growth indicator tube-drug sensitivity test, BMC Complementary and Alternative Medicine, March 2017, Springer Science + Business Media,
DOI: 10.1186/s12906-017-1665-8.
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