What is it about?
Background Prion diseases, also known as transmissible spongiform encephalopathies (TSEs) remain one of the deleterious disorders, which have affected several animal species. Polymorphism of the prion protein (PRNP) gene majorly determines the susceptibility of animals to TSEs. However, only limited studies have examined the variation in PRNP gene in different Nigerian livestock species. Thus, this study aimed to identify the polymorphism of PRNP gene in Nigerian livestock species (including camel, dog, horse, goat, and sheep). This study serves as the first to simultaneously investigate the polymorphism of PRNP gene in Nigerian livestock species and provides relevant information that could be adopted in programs targeted at breeding for prion diseases resistance.
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Why is it important?
This study serves as the first to simultaneously investigate the polymorphism of PRNP gene in Nigerian livestock species and provides relevant information that could be adopted in programs targeted at breeding for prion diseases resistance.
Perspectives
This article provides relevant information that could be adopted in programs targeted at breeding for prion diseases resistance in domestic livestock species.
Associate Professor Adeniyi Charles Adeola
kunming institute of Zoology, Chinese Academy of Sciences
Read the Original
This page is a summary of: Single nucleotide polymorphisms (SNPs) in the open reading frame (ORF) of prion protein gene (PRNP) in Nigerian livestock species, BMC Genomics, February 2024, Springer Science + Business Media,
DOI: 10.1186/s12864-024-10070-2.
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