Clinicopathological characteristics and treatment strategies in early gastric cancer: a retrospective cohort study

  • Hiroaki Ito, Haruhiro Inoue, Haruo Ikeda, Manabu Onimaru, Akira Yoshida, Toshihisa Hosoya, Kosuke Sudo, Nikolas Eleftheriadis, Roberta Maselli, Chiyo Maeda, Yoko Wada, Norimasa Sando, Shigeharu Hamatani, Shin-ei Kudo
  • Journal of Experimental & Clinical Cancer Research, December 2011, Springer Science + Business Media
  • DOI: 10.1186/1756-9966-30-117

Clinicopathological characteristics and treatment strategies in early gastric cancer

What is it about?

The aim of this study was to investigate the optimal treatment strategy for EGC by evaluation of the clinicopathological characteristics. We focused particularly on histological type, because histological type is the only pathological factor which can be definitively diagnosed preoperatively.

Why is it important?

The incidence of nodal metastases was approximately 5% in undifferentiated type mucosal (pT1a) tumors, and higher in submucosal (pT1b) tumors. The sensitivity of preoperative diagnosis of nodal metastases in EGC using computed tomography was relatively low in this study. Therefore at present surgery with adequate lymphadenectomy should be performed as curative treatment for undifferentiated type EGC.

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The following have contributed to this page: Nikolas Eleftheriadis